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Scleroderma Information

Scleroderma (which comes from the Greek meaning ‘hard skin’) is a connective tissue disease that affects the skin and other major internal organs.


It is an autoimmune condition, involving the overproduction of collagen and blood vessel damage. Excess collagen is laid down in these organs which in turn results in scarring and reduced normal function of the affected organs. Scleroderma can cause physical disability and be life threatening as the skin, joints, tendons, and parts of internal organs can all be affected. Autoimmune conditions occur when the body's tissues are attacked by its own immune system. 

1. Systemic sclerosis - the systemic form of scleroderma, which affects the internal organs as well as the skin.

2. Localised scleroderma - a type of scleroderma that affects specific areas of skin and underlying tissues, but does not involve the internal organs.



Comprehensive information on all aspects of scleroderma is available in our booklet:
Understanding and Managing Scleroderma


More detailed information on different problems in scleroderma can be found in our information leaflets.

The Scleroderma Society is affiliated to these not-for-profit organisations:

arma fesca Helplines Partnership National Voices


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